Renal proteinuria is an important complication of chronic renal disease.

The presence of proteinuria is not only a marker of renal injury but also an important independent mediator of progressive renal injury.

Dipsticks are insensitive in documenting proteinuria. The urine protein creatinine ratio offers the best means of assessing the severity of proteinuria and correlates well with 24 hour protein loss.

Healthy cats should have a UPC ratio of <0.2.

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