Peripheral neuropathy is the most common chronic complication of diabetes in cats.

This degenerative disorder typically affects the hindlegs, causing weakness, loss of coordination, inability to jump and a plantigrade stance.

No specific therapy for peripheral neuropathy in cats is available, but intensive blood glucose control decreases the risk and improves clinical signs in humans.

Similarly, aggressive adjustment of insulin therapy may improve nerve function and reverse hindleg weakness and abnormal stance in diabetic cats. However, a cat’s response to the therapy varies and aggressive insulin management can, of course, increase the risk of hypoglycaemia.

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